Pediatric antibody response to community-acquired Staphylococcus aureus infection is directed to Panton-Valentine leukocidin.

نویسندگان

  • Eric L Brown
  • M Gabriela Bowden
  • Rebecca S Bryson
  • Kristina G Hulten
  • Andrea S Bordt
  • Andrea Forbes
  • Sheldon L Kaplan
چکیده

We examined the antibody responses of pediatric patients infected with community-associated Staphylococcus aureus isolates. The data show that patients infected with Panton-Valentine leukocidin (PVL)-positive strains developed a dominant immunoglobulin G anti-PVL antibody response that correlates with markers of inflammation.

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1. Centers for Disease Control and Prevention. Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus—Minnesota and North Dakota, 1997–1999. JAMA. 1999;282:1123–5. DOI: 10.1001/jama. 282.12.1123 2. Tristan A, Bes M, Meugnier H, Lina G, Bozdogan B, Courvalin P, et al. Global distribution of Panton-Valentine leukocidin–positive methicillin-resistant Staphylococc...

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عنوان ژورنال:
  • Clinical and vaccine immunology : CVI

دوره 16 1  شماره 

صفحات  -

تاریخ انتشار 2009